18-75 years old
Accepts healthy patients? No, participants must have primary biliary cholangitis.
Have an elevated alkaline phosphatase (ALP) blood test – this blood test measures the damage to your liver caused by primary biliary cholangitis.
Be unresponsive to ursodeoxycholic acid (UDCA) and/or obeticholicacid (OCA) after 6-months of treatment at a stable dose.