CNP-104 Clinical Trial Primary Biliary Cholangitis
Purpose
The main aim of this study is to see how safe and tolerable CNP-104, an investigational drug, is for people with primary biliary cholangitis and to determine if CNP-104 helps re-balance the immune system to reduce inflammation and restore healthy liver function in adults who do not respond to current treatments. All participants will receive CNP-104 or Placebo intravenously on Day 1 and Day 8.
Key Requirements
Age
18-75 years old
Accepts healthy patients? No, participants must have primary biliary cholangitis.
Have an elevated alkaline phosphatase (ALP) blood test – this blood test measures the damage to your liver caused by primary biliary cholangitis.
Be unresponsive to ursodeoxycholic acid (UDCA) and/or obeticholicacid (OCA) after 6-months of treatment at a stable dose.
Active Clinical Sites
University of California Davis Health
Sacramento, CA
Contact: Jerica Golez
Email: jagolez@ucdavis.edu
Phone: (1) 916-734-8696
Southern California Research Center
Coronado, CA
Contact: Kasey Seyer
Email: kasey@researchscrc.com
Phone: (1) 619-552-0330
Peak Gastroenterology Associates Colorado Springs
Colorado Springs, CO
Contact: Rutva Nakarani
Email: rnakarani@peakgastro.com
Florida Research Institute
Lakewood Ranch, FL
Contact: Myrlande Elichne
Email: myrlande.elichne@fdhs.com
University Florida
Gainesville, FL
Contact: Brianna Foerman
Email: Briana.foerman@medicine.ufl.edu
Phone: (1) 352-273-7285
Mayo Clinic – Florida
Jacksonville, FL
Contact: Reagan Dukes
Email: Dukes.Reagan@mayo.edu
Phone: (1) 904-953-5144
Massachusetts General Hospital
Boston, MA
Contact: Raghav Bordia
Email: RBORDIA@mgh.harvard.edu
Phone: (1) 617-643-7930
Henry Ford Health System
Novi, MI
Contact: Michelle Pierson
Email: mpierso1@hfhs.org
Phone: (1) 248-344-2357
Washington University School of Medicine in St. Louis
St. Louis, MO
Contact: Jennifer Bruns
Email: brunsi@wustl.edu
Phone: (1) 314-747-5366
Duke University Medical Center
Durham, NC
Contact: Nicole Pavlus
Email: Nicole.pavlus@duke.edu
Phone: (1) 919-684-0311
Texas Liver Institute
San Antonio, TX
Contact: Jessica Courtright
Email: jcourtright@txliver.com
Phone: (1) 210-253-3426
University of Virginia
Charlottesville, VA
Contact: Holly McComb
Email: HM8XG@uvahealth.org
Phone: (1) 434-924-2853
Clinicaltrials.gov
Clinical Trial Identifier
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